It is estimated that 1 in 100,000 U.S. residents will develop a salivary malignancy at an average age of 56.6 years of age. The most common malignant histology is Tumors of the submandibular and sublingual salivary glands are more likely to be malignant than those in the parotid. Employment in the rubber industry, exposure to nickel alloys, exposure to silica dust, and the use of kerosene as cooking fuel have been associated with an increased risk of a primary salivary malignancy. A history of skin cancer has also been found to be associated with subsequent development of a primary salivary cancer when it originates in the scalp or face, it also presents a risk for metastases to the parotid gland.
Download: Malignancies of the Major Salivary Glands
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